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Oral Contributed Presentation

PMA

PMA06: Pharmaceutical PAT at 21: Past, Present, Future

Advanced Analytical Techniques Characterizing Water Soluble Polymer Environmental Behavior

Monday, October 6, 2025
4:10 PM - 4:30 PM EDT
Location: Meeting Room #3
In fifteen words or less, explain the significance of this contribution (Novel Aspect).: Advanced analytical techniques clarify water-soluble PVA environmental behavior, which can aid regulation and reduce ambiguity.

Abstract Text: Water Soluble Polymers represent an expanding field of research in the area of their environmental impacts. Yet, lack of standardized classifications and criteria can cause confusion on their effects, especially as it relates to microplastic and real-world assessments. Advanced techniques including SAXS and Dynamic Light Scattering throw light on the behavior of water soluble poly(vinyl alcohol) (PVA) in solution, and characterize its properties vs solid micro- or nano-plastics. Atomic Force Microscopy has been shown to directly demonstrate PVA dissolution to a single molecule level as compared to nano-plastics. A collection of tools could be used for regulatory definition and remove ambiguity in different US states.