Development of a portable inflammation marker detection SPR instrument for astronauts on deep space missions

Wednesday, October 8, 2025

10:30 AM - 10:50 AM EDT

Location: Meeting Room #3

Presenting Author(s)

JM

Jean-François Masson, PhD

Professor
Université de Montréal
Montreal, Quebec, Canada

Non-Presenting Author(s)

CD

Caroline Dubois

Université de Montréal
Montreal, Quebec, Canada
JP

Joelle Pelletier

Université de Montréal
Montreal, Quebec, Canada
DB

Denis Boudreau

Full professor
Université Laval
Quebec city, Quebec, Canada

In fifteen words or less, explain the significance of this contribution (Novel Aspect).: New instrument for SPR monitoring of inflammation markers

Abstract Text:

Over the next few decades, human beings will be called upon to travel outside the Earth's magnetosphere on extended missions to the Moon and Mars. These journeys will increase exposure to cosmic radiation, and thus the potential for radiation-induced disease. Inflammation markers correlate with a range of pathologies from infection to cancer. We are developing a small, portable SPR instrument based on surface plasmon resonance and microfluidics to measure a panel of inflammation markers from a drop of blood. The concept is based on a disposable cartridge in which the drop of blood reacts with the surface of the device, and for which the concentration of markers is revealed by reagents inserted in the cartridge. The presentation will showcase the technological advances made to date, and demonstrate the technology's potential for astronaut health monitoring.